{"id":12880,"date":"2024-06-11T09:25:56","date_gmt":"2024-06-11T09:25:56","guid":{"rendered":"https:\/\/olmix.com\/?p=12880"},"modified":"2024-07-01T12:20:00","modified_gmt":"2024-07-01T12:20:00","slug":"combattre-mycotoxines-volaille-decontaminant-algoclay","status":"publish","type":"post","link":"https:\/\/olmix.com\/fr\/combattre-mycotoxines-volaille-decontaminant-algoclay\/","title":{"rendered":"Combattre les mycotoxines en volaille avec un d\u00e9contaminant \u00e0 base d\u2019Algoclay"},"content":{"rendered":"[vc_row type=\u00a0\u00bbin_container\u00a0\u00bb full_screen_row_position=\u00a0\u00bbmiddle\u00a0\u00bb column_margin=\u00a0\u00bbdefault\u00a0\u00bb column_direction=\u00a0\u00bbdefault\u00a0\u00bb column_direction_tablet=\u00a0\u00bbdefault\u00a0\u00bb column_direction_phone=\u00a0\u00bbdefault\u00a0\u00bb scene_position=\u00a0\u00bbcenter\u00a0\u00bb constrain_group_4=\u00a0\u00bbyes\u00a0\u00bb text_color=\u00a0\u00bbdark\u00a0\u00bb 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icon_family=\u00a0\u00bbfontawesome\u00a0\u00bb icon_style=\u00a0\u00bbdefault\u00a0\u00bb icon_color_type=\u00a0\u00bbcolor_scheme\u00a0\u00bb icon_color=\u00a0\u00bbExtra-Color-1″ icon_padding=\u00a0\u00bb0px\u00a0\u00bb pointer_events=\u00a0\u00bball\u00a0\u00bb icon_fontawesome=\u00a0\u00bbfa fa-clock-o\u00a0\u00bb icon_size=\u00a0\u00bb15″ margin_right=\u00a0\u00bb7px\u00a0\u00bb margin_top=\u00a0\u00bb1px\u00a0\u00bb][vc_column_text]Reading Time:<\/span> 3<\/span> minutes<\/span><\/span>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=\u00a0\u00bbdefault\u00a0\u00bb column_direction=\u00a0\u00bbdefault\u00a0\u00bb column_direction_tablet=\u00a0\u00bbdefault\u00a0\u00bb column_direction_phone=\u00a0\u00bbdefault\u00a0\u00bb top_padding=\u00a0\u00bb2%\u00a0\u00bb constrain_group_1=\u00a0\u00bbyes\u00a0\u00bb bottom_padding=\u00a0\u00bb2%\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb row_position=\u00a0\u00bbdefault\u00a0\u00bb row_position_tablet=\u00a0\u00bbinherit\u00a0\u00bb row_position_phone=\u00a0\u00bbinherit\u00a0\u00bb overflow=\u00a0\u00bbvisible\u00a0\u00bb pointer_events=\u00a0\u00bball\u00a0\u00bb][vc_column_inner column_padding=\u00a0\u00bbpadding-2-percent\u00a0\u00bb column_padding_tablet=\u00a0\u00bbinherit\u00a0\u00bb column_padding_phone=\u00a0\u00bbinherit\u00a0\u00bb column_padding_position=\u00a0\u00bbleft\u00a0\u00bb left_margin=\u00a0\u00bb7px\u00a0\u00bb column_element_direction_desktop=\u00a0\u00bbdefault\u00a0\u00bb column_element_spacing=\u00a0\u00bbdefault\u00a0\u00bb desktop_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb tablet_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb phone_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb background_color_opacity=\u00a0\u00bb1″ background_hover_color_opacity=\u00a0\u00bb1″ column_backdrop_filter=\u00a0\u00bbnone\u00a0\u00bb column_shadow=\u00a0\u00bbnone\u00a0\u00bb column_border_radius=\u00a0\u00bbnone\u00a0\u00bb column_link_target=\u00a0\u00bb_self\u00a0\u00bb overflow=\u00a0\u00bbvisible\u00a0\u00bb gradient_direction=\u00a0\u00bbleft_to_right\u00a0\u00bb overlay_strength=\u00a0\u00bb0.3″ width=\u00a0\u00bb1\/1″ tablet_width_inherit=\u00a0\u00bbdefault\u00a0\u00bb animation_type=\u00a0\u00bbdefault\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb border_type=\u00a0\u00bbadvanced\u00a0\u00bb border_left_desktop=\u00a0\u00bb1″ column_border_color=\u00a0\u00bb#269756″ column_border_style=\u00a0\u00bbsolid\u00a0\u00bb column_padding_type=\u00a0\u00bbdefault\u00a0\u00bb gradient_type=\u00a0\u00bbdefault\u00a0\u00bb][vc_column_text el_class=\u00a0\u00bbmed\u00a0\u00bb]Le d\u00e9oxynival\u00e9nol (DON) est l’une des mycotoxines les plus r\u00e9pandues dans le monde. Il peut alt\u00e9rer la morphologie intestinale et provoquer un stress oxydatif h\u00e9patique chez le poulet de chair, impactant ainsi leurs performances zootechniques.<\/p>\n

Ces cons\u00e9quences peuvent se produire m\u00eame \u00e0 des niveaux inf\u00e9rieurs au seuil recommand\u00e9 de 5 mg DON\/kg d’aliment (Commission europ\u00e9enne). Plusieurs \u00e9tudes sur des poulets de chair ont montr\u00e9 que le DON diminue la hauteur des villosit\u00e9s et g\u00e9n\u00e8re des l\u00e9sions intestinales \u00e0 des niveaux aussi bas que 1,9 mg\/kg d\u2019aliment. En collaboration avec l’Universit\u00e9 de Gand (Belgique) et Schothorst Feed Research (Pays-Bas), deux essais ont \u00e9t\u00e9 men\u00e9s pour \u00e9valuer la capacit\u00e9 d’un d\u00e9contaminant \u00e0 base d’algoclay (MT.X+\u00ae<\/sup>, Olmix) \u00e0 r\u00e9duire l’exposition \u00e0 plusieurs mycotoxines chez le poulet de chair et am\u00e9liorer leurs m\u00e9tabolismes intestinal et h\u00e9patique lorsqu’ils sont naturellement expos\u00e9s au DON.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner column_margin=\u00a0\u00bbdefault\u00a0\u00bb column_direction=\u00a0\u00bbdefault\u00a0\u00bb column_direction_tablet=\u00a0\u00bbdefault\u00a0\u00bb column_direction_phone=\u00a0\u00bbdefault\u00a0\u00bb top_padding=\u00a0\u00bb2%\u00a0\u00bb constrain_group_1=\u00a0\u00bbyes\u00a0\u00bb bottom_padding=\u00a0\u00bb2%\u00a0\u00bb text_align=\u00a0\u00bbleft\u00a0\u00bb row_position=\u00a0\u00bbdefault\u00a0\u00bb row_position_tablet=\u00a0\u00bbinherit\u00a0\u00bb row_position_phone=\u00a0\u00bbinherit\u00a0\u00bb overflow=\u00a0\u00bbvisible\u00a0\u00bb pointer_events=\u00a0\u00bball\u00a0\u00bb][vc_column_inner column_padding=\u00a0\u00bbno-extra-padding\u00a0\u00bb column_padding_tablet=\u00a0\u00bbinherit\u00a0\u00bb column_padding_phone=\u00a0\u00bbinherit\u00a0\u00bb column_padding_position=\u00a0\u00bball\u00a0\u00bb column_element_direction_desktop=\u00a0\u00bbdefault\u00a0\u00bb column_element_spacing=\u00a0\u00bbdefault\u00a0\u00bb desktop_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb tablet_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb phone_text_alignment=\u00a0\u00bbdefault\u00a0\u00bb background_color_opacity=\u00a0\u00bb1″ background_hover_color_opacity=\u00a0\u00bb1″ column_backdrop_filter=\u00a0\u00bbnone\u00a0\u00bb column_shadow=\u00a0\u00bbnone\u00a0\u00bb column_border_radius=\u00a0\u00bbnone\u00a0\u00bb column_link_target=\u00a0\u00bb_self\u00a0\u00bb overflow=\u00a0\u00bbvisible\u00a0\u00bb gradient_direction=\u00a0\u00bbleft_to_right\u00a0\u00bb overlay_strength=\u00a0\u00bb0.3″ width=\u00a0\u00bb1\/1″ tablet_width_inherit=\u00a0\u00bbdefault\u00a0\u00bb animation_type=\u00a0\u00bbdefault\u00a0\u00bb bg_image_animation=\u00a0\u00bbnone\u00a0\u00bb border_type=\u00a0\u00bbsimple\u00a0\u00bb column_border_width=\u00a0\u00bbnone\u00a0\u00bb column_border_style=\u00a0\u00bbsolid\u00a0\u00bb][vc_column_text]Le premier essai \u00e9tait un mod\u00e8le toxicocin\u00e9tique dans lequel le DON, l’OTA et l’AFB1 ont \u00e9t\u00e9 administr\u00e9s oralement en une seule fois \u00e0 des poulets de chair, pour atteindre une contamination en mycotoxine \u00e9quivalente \u00e0 5 mg\/kg\u00a0; 2,5 mg\/kg et 20 mg\/kg d’aliment, respectivement. Un groupe n’a pas re\u00e7u le d\u00e9contaminant (groupe t\u00e9moin<\/em>) et l’autre groupe a re\u00e7u le d\u00e9contaminant \u00e0 base d’algoclay \u00e0 2,5 g\/kg d’aliment (groupe MT.X+\u00ae<\/sup><\/em>). Des \u00e9chantillons de sang ont \u00e9t\u00e9 pr\u00e9lev\u00e9s en s\u00e9rie pour mesurer les concentrations plasmatiques de DON-3S (DON-3 sulfate, principal m\u00e9tabolite du DON chez la volaille), d’OTA et d’AFB1. Les r\u00e9sultats ont montr\u00e9 que MT.X+\u00ae<\/sup> a r\u00e9duit l’exposition au DON des poulets de chair. Le niveau plasmatique de DON-3S a \u00e9t\u00e9 r\u00e9duit de 40 % dans le Groupe MT.X+\u00ae<\/sup> (figure 1).[\/vc_column_text][image_with_animation image_url=\u00a0\u00bb12897″ image_size=\u00a0\u00bbfull\u00a0\u00bb animation_type=\u00a0\u00bbentrance\u00a0\u00bb animation=\u00a0\u00bbNone\u00a0\u00bb animation_movement_type=\u00a0\u00bbtransform_y\u00a0\u00bb hover_animation=\u00a0\u00bbnone\u00a0\u00bb alignment=\u00a0\u00bb\u00a0\u00bb border_radius=\u00a0\u00bbnone\u00a0\u00bb box_shadow=\u00a0\u00bbnone\u00a0\u00bb image_loading=\u00a0\u00bbdefault\u00a0\u00bb max_width=\u00a0\u00bb100%\u00a0\u00bb max_width_mobile=\u00a0\u00bbdefault\u00a0\u00bb][vc_column_text]Figure 1 :<\/span><\/em>\u00a0Concentration plasmatique moyenne de DON-3S, principal m\u00e9tabolite du DON, apr\u00e8s administration orale de DON en une seule fois (0,5 mg\/kg PV).<\/span><\/i>[\/vc_column_text][vc_column_text]Les r\u00e9sultats ont montr\u00e9 que MT.X+\u00ae<\/sup> a consid\u00e9rablement r\u00e9duit l’exposition des poulets de chair \u00e0 l’OTA, puisque son niveau dans le sang a diminu\u00e9 de 44 %. En ce qui concerne l’AFB1, une r\u00e9duction plus importante a \u00e9t\u00e9 observ\u00e9e, le taux sanguin d\u2019AFB1 chez les poulets suppl\u00e9ment\u00e9s avec MT.X+\u00ae<\/sup> \u00a0ont \u00e9t\u00e9 r\u00e9duit de 64% par rapport aux poulets t\u00e9moins.<\/p>\n

Dans le deuxi\u00e8me essai, deux r\u00e9gimes ont \u00e9t\u00e9 utilis\u00e9s, le groupe t\u00e9moin<\/em> a re\u00e7u un r\u00e9gime peu contamin\u00e9 par le DON (~0,2 mg de DON\/kg). Le deuxi\u00e8me r\u00e9gime \u00e9tait naturellement contamin\u00e9 par le DON (~3,0 mg DON\/kg) et a \u00e9t\u00e9 distribu\u00e9 \u00e0 deux groupes exp\u00e9rimentaux\u00a0: le groupe DON<\/em> a re\u00e7u ce r\u00e9gime sans d\u00e9contaminant, et le groupe MT.X+\u00ae<\/sup><\/em> a re\u00e7u le m\u00eame aliment suppl\u00e9ment\u00e9 avec 2,0 g de MT.X+\u00ae<\/sup>\/kg. L’exposition alimentaire \u00e0 3 mg\/kg de DON a provoqu\u00e9 des l\u00e9sions et un raccourcissement des villosit\u00e9s dans le j\u00e9junum. De plus, un stress oxydatif a eu lieu dans le foie. Ces effets n’ont pas \u00e9t\u00e9 observ\u00e9s lorsque MT.X+\u00ae<\/sup> a \u00e9t\u00e9 ajout\u00e9 au r\u00e9gime DON.[\/vc_column_text][image_with_animation image_url=\u00a0\u00bb12895″ image_size=\u00a0\u00bbfull\u00a0\u00bb animation_type=\u00a0\u00bbentrance\u00a0\u00bb animation=\u00a0\u00bbNone\u00a0\u00bb animation_movement_type=\u00a0\u00bbtransform_y\u00a0\u00bb hover_animation=\u00a0\u00bbnone\u00a0\u00bb alignment=\u00a0\u00bb\u00a0\u00bb border_radius=\u00a0\u00bbnone\u00a0\u00bb box_shadow=\u00a0\u00bbnone\u00a0\u00bb image_loading=\u00a0\u00bbdefault\u00a0\u00bb max_width=\u00a0\u00bb100%\u00a0\u00bb max_width_mobile=\u00a0\u00bbdefault\u00a0\u00bb][vc_column_text]Tableau 1 :\u00a0Histomorphom\u00e9trie du jejunum \u00e0 J37.<\/i>[\/vc_column_text][vc_column_text]En r\u00e9sum\u00e9, l’\u00e9tude d\u00e9montre que la technologie algoclay test\u00e9e peut r\u00e9duire l’exposition syst\u00e9mique des poulets de chair au d\u00e9oxynival\u00e9nol (40 %), \u00e0 l’ochratoxine A (44 %) et \u00e0 l’aflatoxine B1 (64 %), sur la base d’un mod\u00e8le toxicocin\u00e9tique. De plus, les dommages caus\u00e9s par environ 3 mg\/kg de d\u00e9oxynival\u00e9nol (DON) sur la morphologie intestinale et le stress oxydatif dans le foie des poulets de chair ont \u00e9t\u00e9 \u00e9vit\u00e9s gr\u00e2ce \u00e0 une suppl\u00e9mentation alimentaire avec le d\u00e9contaminant \u00e0 base d’algoclay.[\/vc_column_text][divider line_type=\u00a0\u00bbFull Width Line\u00a0\u00bb line_thickness=\u00a0\u00bb1″ divider_color=\u00a0\u00bbaccent-color\u00a0\u00bb custom_height=\u00a0\u00bb20″][vc_column_text]R\u00e9f\u00e9rence: Gallissot, M.; Rodriguez, M.A.; Devreese, M.; Van herteryck, I.; Molist, F. and Santos, R. 2024. An Algoclay-Based Decontaminant Decreases Exposure to Aflatoxin B1, Ochratoxin A, and Deoxynivalenol in a Toxicokinetic Model, as well as Supports Intestinal Morphology, and Decreases Liver Oxidative Stress in Broiler Chickens Fed a Diet Naturally Contaminated with Deoxynivalenol. Toxins 16: 207. https:\/\/pubmed.ncbi.nlm.nih.gov\/38787059\/<\/a><\/span><\/i>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

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